Who We Are
John H Van Drie is a pharma industry veteran, with over 20 years drug discovery experience. His most notable contributions have been in
anti-virals (Hepatitis C NS3 protease inhibitors, HIV), antibiotics (oxazolidinone antibiotics), CNS (various biogenic amine GPCR's),
and oncology (primarily kinases).
Before founding Van Drie Research LLC in 2007, he was Director of the CADD group at Novartis, and a member of the Global Discovery Chemistry Leadership Team. Prior to that, he worked at Vertex; before that, Pharmacia (originally the Upjohn Company); he was a founding member of BioCAD, a Silicon Valley startup that developed the Catalyst software for drug design, still marketed by Accelrys.
John is an internationally-recognized expert in the area of computer-aided drug design (CADD), and was the Chair of the first Gordon Conference on CADD. He is one of the pioneers of virtual screening, and pharmacophore-based methods.
He studied theoretical chemistry as an NSF Fellow with W. A. Goddard III at Caltech; his PhD thesis, "Information Theory and Quantum Mechanics", was the first-ever exploration of that topic. He also studied with I. Prigogine as a BAEF Fellow at the Univ. Libre de Bruxelles.
He has been active in drug discovery since the mid-1980's. Here are his publications in the biomedical arena that have been indexed in PubMed.
Before founding Van Drie Research LLC in 2007, he was Director of the CADD group at Novartis, and a member of the Global Discovery Chemistry Leadership Team. Prior to that, he worked at Vertex; before that, Pharmacia (originally the Upjohn Company); he was a founding member of BioCAD, a Silicon Valley startup that developed the Catalyst software for drug design, still marketed by Accelrys.
John is an internationally-recognized expert in the area of computer-aided drug design (CADD), and was the Chair of the first Gordon Conference on CADD. He is one of the pioneers of virtual screening, and pharmacophore-based methods.
He studied theoretical chemistry as an NSF Fellow with W. A. Goddard III at Caltech; his PhD thesis, "Information Theory and Quantum Mechanics", was the first-ever exploration of that topic. He also studied with I. Prigogine as a BAEF Fellow at the Univ. Libre de Bruxelles.
He has been active in drug discovery since the mid-1980's. Here are his publications in the biomedical arena that have been indexed in PubMed.